Laboratory of Cardiovascular Fluid Dynamics
People Facilities Publications Gallery Collaborations Forms and Resources	Notice: If you download the .pdf files below, you recognize that it is for your personal use only. Book Chapter Kadem L. Aortic Stenosis and Systemic Hypertension:  See Beyond the Valve. Heart Valves: Disorders, Repair, and Replacement, Nova Science Publishers, 2009. Journal Articles Z. Keshavarz-Motamed, J. Garcia, N. Maftoon, E. Bedard, P. Chetaille, L. Kadem. A New Approach for the Evaluation of the Severity of Coarctation of the Aorta Using Doppler Velocity Index: In vitro Validation and Clinical Implications. Accepted in Journal of Biomechanics (2012) Mandour A, Fayed M, Ait Abderrahmane H, Ng HD, Kadem L, Vatistas GH Symmetry-Breaking of Interfacial Polygonal Patterns and Synchronization of Travelling Waves within a Hollow-Core Vortex Chaotic Modeling and Simulation 2012; 1: 257-271. Z. Keshavarz-Motamed, J. Garcia, P. Pibarot, E. Larose, L. Kadem. Modeling the impact of concomitant aortic stenosis and coarctation of the aorta on left ventricular workload. Journal of Biomechanics 2011; 44: 2817-2825 Saleh W, Bowden RC, Hassan IG, Kadem L. Theoretical Analysis of the Onset of Gas Entrainment from a Stratified Region through Multiple Branches International Journal of Multiphase Flow 2011; 37(10): 1348-1357 Rafiqul Haque M, Fayed M, Gunter A; Smadi O, Kadem L, Ng HD. Numerical Simulation and Flow Visualization Using Soap Film of the Self-Organized Vortex Structure in the Wake of an Array of Cylinders Journal of Visualization 2011; 14(4): 311-314 Garcia J, Kadem L, E. Larose, M.A. Clavel, P. Pibarot. Comparison between Cardiovascular Magnetic Resonance Imaging and Transthoracic Doppler Echocardiography for the Estimation of Valve Effective Orifice Area in Patients with Aortic Stenosis. Journal of Cardiovascular Magnetic Resonance 2011; 13:25 Gaillard E, Kadem L, Pibarot P, Durand LG. Effect of a concomitant asymmetric septal hypertrophy on the assessment of the severity of an aortic valve stenosis: an in-vitro study Accepted in Journal of Heart Valve Disease (2011) Gunter A, Smadi O, Kadem L, Ng HD. Visualization of an imploding circular wave front and the formation of a central vertical jet Journal of Visualization 2011; 14(1): 19-22 Saleh W, Bowden RC, Hassan IG, Kadem L. Stereo Particle Image Velocimetry applied to Stratified Two-phase Headers: Techniques and Challenges Experimental Thermal and Fluid Science 2011; 35: 82-92 Gaillard E, Kadem L, Durand LG. A Simple Non-Invasive Method to Predict Mitral Valve Geometric Orifice Area Following an Edge to Edge Repair. Journal of Heart Valve Disease 2011; 1: 1-5 Keshavarz-Motamed Z and Kadem L. 3D Pulsatile Flow in a Curved Tube with Coexisting Model of Aortic Stenosis and Coarctation of the Aorta. Medical Engineering and Physics 2010; 33(3): 315-324 Gaillard E, Kadem L, Pibarot P, Durand LG. Optimization of Doppler echocardiographic velocity measurements using an automatic contour detection method. Ultrasound in Medicine and Biology 2010; 36(9): 1513-1524. Saleh W, Bowden RC, Hassan IG, Kadem L. Two-Phase Flow Structure in Dual Discharging - Stereo PIV Measurements. Experimental Thermal and Fluid Science 2010; 34: 1016–1028 Gaillard E, Kadem L, Pibarot P, Durand LG. In vitro Investigation of the Impact of aortic valve stenosis severity on left coronary artery flow.  Journal of Biomechanical Engineering 2010; 132: 044502 – 1:4. Smadi O, Hassan IG, Pibarot P, Kadem L. Numerical and experimental investigations of pulsatile blood flow pattern through a dysfunctional mechanical heart valve. Journal of Biomechanics 2010; 43(8): 1565-1572. Keshavarz-Motamed Z, Kadem L, Dolatabadi A. Effects of Dynamic Contact Angle on Numerical Modeling of Electrowetting in Parallel Plate Microchannels. Microfluidic and Nanofluidic 2010; 8: 47-56. Tanné D, Bertrand E, Kadem L, Pibarot P, Rieu R. Assessment of left heart and pulmonary circulation flow dynamics by a new pulsed mock circulatory system. Experiments in Fluids 2010; 5: 837-850. Smadi O, Fenech M, Hassan IG, Kadem L. Flow Through a Defective Mechanical Heart Valve: a Steady Flow Analysis. Medical Engineering Physics 2009; 31(3): 295-305. [pdf] Saleh W, Bowden RC, Hassan IG, Kadem L. A Hybrid model to Predict the Onset of Gas Entrainment with Surface Tension Effect. Journal of Fluid Engineering 2009; 131: 011305-1-10. Tanné D, Kadem L, Rieu R, Pibarot P. Hemodynamic Impact of Mitral Prosthesis-Patient Mismatch: An in Silico Study. Journal of Applied Physiology 2008; 105(6):1916-26. [pdf] Garcia D, Pibarot P, Kadem L, Durand LG. Respective Impacts of Aortic Stenosis and Systemic Hypertension on the Left Ventricular Hypertrophy. Journal of Biomechanics 2007; 40 (5): 972-980. [pdf] Kadem L, Garcia D. Are we using the right fluid mechanics principles? Ann Thorac Surg. 2007; 83(1):354 [letter to editor] Garcia D, Kadem L, Savéry D, Pibarot P, Durand LG. Analytical modeling of instantaneous maximal transvalvular pressure gradient in aortic stenosis. J Biomech. 2006; 39(16): 3036-3044. [pdf] Garcia D, Kadem L. What do you mean by aortic valve area: geometric orifice area, effective orifice area or Gorlin area? J Heart Valve Dis. 2006; 15 :601-608. [pdf] Kadem L, Garcia D, Durand LG, Rieu R, Dumesnil JG, Pibarot P. Value and limitations of peak-to-peak gradient for evaluation of aortic stenosis. J Heart Valve Dis. 2006; 15: 609-616.[pdf] Blais C, Burwash IG, Mundigler G, Dumesnil JG, Loho N, Rader F, Baumgartner H, Beanlands RS, Chayer B, Kadem L, Garcia D, Durand LG, Pibarot P. The Projected Valve Area at Normal Flow Rate Improves the Assessment of Stenosis Severity in Patients with Low Flow, Low Gradient Aortic Stenosis. The Multicenter TOPAS (Truly Or Pseudo Severe Aortic Stenosis) Study. Circulation 2006; 113:711-721. This article has been commented in an editorial written by A. Grayburn. [pdf] [editorial] Kadem L, Rieu R, Dumesnil JG, Durand LG, Pibarot P. Flow Dependent Changes in Doppler Derived Aortic Valve Effective Orifice Area are Real and not Due to Artifact. Journal of American College of Cardiology 2006; 47(1): 131-137. This article has been commented in an editorial written by H. Baumgartner. [pdf] Kadem L, Knapp Y, Pibarot P, Durand LG, Rieu R. A New Experimental Technique for the Determination of Effective Orifice Area based on the Acoustical Source Term. Experiments in Fluids 2005; 39: 1051-1060. [pdf] Briand M, Dumesnil JG, Kadem L, Tongue A, Rieu R, Garcia D, Pibarot P. Reduced Systemic Arterial Compliance Impacts Significantly on LV Afterload and Function in Aortic Stenosis: Implications for Diagnosis and Treatment.Journal of American College of Cardiology 2005; 46(2): 291-298. This article has been commented in an editorial written by KL. Peterson. [pdf] [editorial] Mouret F, Kadem L, Bertrand E, Dumesnil JG, Pibarot P, Rieu R. Mitral Prosthesis Opening and Flow Dynamics in a Model of Left Ventricle: an in vitro Study on a Monoleaflet Mechanical Valve. Cardiovascular Engineering 2005; 5(1):13-20. [pdf] Kadem L, Dumesnil JG, Rieu R, Durand LG, Garcia D, Pibarot P. Impact of systemic hypertension on the assessment of aortic stenosis. Heart. 2005; 91(3):354-61. This article has been commented in an editorial written by J. Bermejo. [pdf] [editorial] Garcia D, Dumesnil JG, Durand LG, Kadem L, Pibarot P. Discrepancies between catheter and Doppler estimates of valve effective orifice area can be predicted from the pressure recovery phenomenon. Practical implications with regards to quantification of aortic stenosis severity. Journal of American College of Cardiology 2002; 41(3):435-442.This article has been commented in an editorial written by RA. Levine. [pdf] [editorial] Kadem L, Pibarot P, Dumesnil JG, Mouret F, Garitey V, Durand LG, Rieu R. Independent Contribution of Left Ventricular Ejection Time to the Mean Gradient in Aortic Stenosis. Journal of Heart Valve Disease 2002; 11(5):615-23. [pdf] [download all our papers]