Microscopic fungi and their metabolites in dwellings - a bioassay study
Pieckov¨˘, E., Jesensk¨˘, M. Z. and Wilikins, K.
2001
In "Bioaerosols, Fungi and Mycotoxins: Health Effects, Assessment, Prevention and Control", Edited by Johanning, E., Boyd Printing, Albany, New York
indoor environment, chronic respiratory symptoms, microscopic fungi, fungal chloroform-extractable endo- and exometabolites, cilliated epithelium, tracheal organ cultures, ciliostatic effect.
Pieckov¨˘, E., Jesensk¨˘, M. Z. and Wilikins, K., (2001), "Microscopic fungi and their metabolites in dwellings - a bioassay study", In "Bioaerosols, Fungi and Mycotoxins: Health Effects, Assessment, Prevention and Control", Edited by Johanning, E., Boyd Printing, Albany, New York.
| Abstract
The ciliostatic effect of chloroform-extractable endo- and exocellular metabolites of the most frequently isolated fungal strains from growth in dwellings: Alternaria sp., Aspergillus glaucus group, A. versicolor, Cladosporium sphaerospermum, Penicillium sp., P. chrysogenum, Stachybotrys chartarum, Trichoderma viride and Ulocladium sp. was studied on tracheal cilia from day old chicks in vitro. Biomass extracts from Alternaria sp. and A. versicolor as well as exocellular extracts from P. chrysogenum, S. chartarum I, T. viride and Ulocladium sp. stopped cilia movement during the first 24 hours. Biomass extracts of P. chrysogenum, S. chartarum I and T. viride as well as media extracts from Alternaria sp., C. sphaerospermum and Penicillium sp. stopped cilia movement between 24 and 48 hours. Between 48 and 72 hours the biomass extract of an A. glaucus gr. isolate and media extracts of A. versicolor and S. chartarum II showed activity while the other extracts (cellular from C. sphaerospermum, S. chartarum II and Ulocladium sp. and media one from A. glaucus gr.) showed no activity. The results are discussed in relationship with health status of people living/working in moldy buildings. |
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Related Concepts
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Related Resources:
 Bioaerosols, Fungi and Mycotoxins, Ed. by Johanning, E.
"papers presented at the September, 1998 Third International Conference in Saratoga Springs, New York. clinical and epidemiological studies and technical reports on an emerging public health topic affecting people in indoor environments at work and at home."
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