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Microfluidics
One of the fundamental BioMEMS researches carried out at the Optical Bio-Microsystems Laboratory is to design, model, analyze, fabricate, characterize, test and develop a prototype of microfluidic chip on silicon and polymer platforms for the optical detection of biological species through external attachment of a spectrometer on chip. A strategic packaging technology for silicon based microfluidic chips was also developed, for enhanced fluorescence based biodetection.
(a) SEM of anisotropically etched microfluidic channel (b) Fully packaged microfluidic chip (c) FEM result of fluid flow (d) Results of flow visualization carried out for one of the microfluidic channels.
Microfluidic Testing facility: Particle Image Velocimetry (PIV) and Particle Tracking Velocimetry (PTV)
It is possible to view and estimate the flow behavior inside the microchannels. This facility is useful in estimating the residence time, bio affinity, fluid velocities, stagnant zones, optimum fluid conditions for improved bio-affinity, etc.
Predicted and experimental variation of streamline velocity tracked along the mid-axis for both circular and triangular microchambers using PTV method.
Velocity field contours in triangular microchambers with (a) Predicted (b) Experimental streak lines (c) Epifluorescence video using PIV method at low velocities.
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