Journal Publications

Citation Data: Google Scholar and Research Gate profile.


*Co-first author; #Co-corresponding author


  1. Leclerc, L.M.Y., Soffer, G., Kwan, D.H., Shih, S.C.C., A Fucosyltransferase Inhibition Assay using Image-Analysis and Digital Microfluidics Biomicrofluidics (2019), 13, 034106 [pdf] [link]
  2. Moazami, E., Perry, J.M., Soffer, G., Husser, M.C., Shih, S.C.C., Integration of World-to-Chip Interfaces with Digital Microfluidics for Bacterial Transformation and Enzymatic Assays Analytical Chemistry (2019), 91, 5159-5168 [pdf] [link]
  3. Ahmadi, F., Samlali, K., Shih, S.C.C., An integrated droplet-digital microfluidics system for on-demand droplet creation, mixing, incubation, and sorting Lab Chip (2019), 19, 524-535 [pdf] [link]
  4. Sinha, H., Quach, A.B.V., Vo, P.Q.N., Shih, S.C.C., An automated microfluidic gene-editing platform for deciphering cancer genes Lab on Chip (2018), 18, 2300-2312 [pdf] [link] Highlighted in the media: SLAS, La Presse, Concordia #1, Concordia #2
  5. Husser, M.C., Vo, P.Q.N., Sinha, H., Ahmadi, F., Shih, S.C.C., An Automated Induction Microfluidics System for Synthetic Biology ACS Synthetic Biology (2018), 7, 933-944 [pdf] [link]
  6. Vo, P.Q.N., Husser, M.C., Ahmadi, F., Sinha, H., Shih, S.C.C., Image-based Feedback and Analysis System for Digital Microfluidics. Lab on Chip (2017), 17, 3437-3446 [pdf] [link]

  7. Pre-Concordia Publications

  8. Heinemann, J., Deng, K., Shih, S.C.C., Gao, J. Adams, P.D., Singh, A.K., Northen, T. R., On-chip integration of droplet microfluidics and nanostructure-initiator mass spectrometry for enzyme screening. Lab on Chip (2017), 17, 323-331 [pdf] [link]
  9. Shih, S.C.C.#, Moreas, C., Next Generation Tools to Accelerate the Synthetic Biology Process. Intergr. Biol. (2016), 8, 585-588 [pdf] [link]
  10. Gach, P.C., Shih, S.C.C., Sustarich, J., Keasling, J.D., Adams, P.D., Hillson, N.J., Singh, A.K., A Droplet Microfluidic Platform for Automating Genetic Engineering. ACS Synthetic Biology (2016), 4, 1151-1164 [pdf] [link]
  11. Shih, S.C.C#, Goyal, G., Kim, P.W., Koutsoubelis, N., Keasling, J.D., Adams, P.D., Hillson, N.J., Singh, A.K.#., A Versatile Microfluidic Device for Automating Synthetic Biology. ACS Synthetic Biology (2015), 10, 1151-1164 [pdf] [link][Cover page of journal ]
  12. Shih, S.C.C., Gach, P.C., Sustarich, J., Adams, P.D., Singh, A.K., A droplet-to-digital (D2D) microfluidic device for screening single cells. Lab on chip (2015), 15, 225-236. [pdf] [link] (Impact factor: 5.748)
  13. Shih, S.C.C., Mufti, N., Chamberlain, M.D., Kim, J., Wheeler, A.R., A Droplet-Based Screen for Wavelength-Dependent Lipid Production in Algae. Energy & Environmental Science (2014), 7, 2366-2375. [pdf] [link] (Impact factor: 15.49)  Highlighted in the media: Chemistry World, Scientific American
  14. Lafrenière N.M., Shih S.C.C., Abu-Rabie P., Spooner N., and Wheeler A.R., Multiplexed Extraction and Analysis of Pharmaceuticals from Dried Blood Spots using Digital Microfluidics. Bioanalysis (2014), 3, 307-318. [pdf] [link] (Impact factor: 3.253)
  15. Shih S.C.C., Barbulovic-Nad I., Yang X., Fobel R., and Wheeler A.R., Digital microfluidics with impedance sensing for integrated cell culture and analysis. Biosensors and Bioelectronics (2013), 42, 314-320. (Impact factor: 6.037) [pdf] [link]
  16. Shih S.C.C., Yang H., Jebrail M.J., Fobel R., McIntosh N., Al-Dirbashi O.Y., Chakraborty P., and Wheeler A.R., Digital Microfluidics coupled to nanoelectrospray ionization mass spectrometry for succinylacetone analysis in dried blood spots. Analytical Chemistry (2012), 84, 3731-3738. [pdf] [linkCover page of journal 
  17. Shih S.C.C., Fobel R., Kumar P., and Wheeler A.R,  A feedback control system for high-fidelity digital microfluidics. Lab on Chip (2011), 11, 535-540. [pdf] [link] (Impact factor: 5.748)
  18. Au, S.H.*, Shih, S.C.C.*, and Wheeler A.R. Integrated Microbioreactor for the Culture and Analysis of Bacteria, Algae and Yeast. Biomedical Microdevices (2011), 13, 41-50. [pdf] [link] (Impact factor: 2.718)
  19. Jebrail, M.J.*, Luk, V.N.*, Shih, S.C.C.*, Fobel, R., Ng, A.H.C, Yang, H., Freire, S.L.S. Wheeler, A.R. Digital Microfluidics for Automated Proteomic Processing J. Vis. Res. (JOVE) (2009), Only available as DOI: 10.3791/1603 [pdf] [link] **Learn microfluidic fabrication then click the link above**
  20. Shih S.C.C.*, Stoica, I.*, and Goto, N.K. Investigation of the utility of selective methyl protonation for determination of membrane protein structure. J. Biol NMR (2009), 42:49-58. [pdf] [link]
  21. Wu, Y., Shih S.C.C., and Goto, N.K. Probing the structure of the Ff bacteriophage major coat protein transmembrane helix dimer by solution NMR. BBA - Biomembranes (2007), 1768: 3206-3215. [pdf] [link]

Thesis dissertations: Master and Ph.D


Conference Presentations (L=Lecture; P=Poster)

  1. Synthetic Biology: Engineering, Evolution & Design, Boston, MA, US, Jun 2015. "A versatile microfluidic device for synthetic biology" (L).
  2. Synthetic Biology: Engineering, Evolution & Design, Boston, MA, US, Jun 2015. "Synthetic Biology in a Chip: A Digital Microfluidic Platform for Cell Transformation, Culture and Expression" (P).
  3. Micro Total Analysis Systems Symposium, San Antonio, TX, US, Oct 2014. “A droplet-to-digital microfluidics device for screening single cells” (L).
  4. Micro Total Analysis Systems Symposium, San Antonio, TX, US, Oct 2014. “Towards synthetic biology in a chip: An Integrated digital microfluidic platform or transformation, culture, and expression” (P).
  5. 96th Canadian Chemistry Conference and Exhibition, Quebec, QE, Canada, May 2013 “Multiplexed Extraction and Analysis of Pharmaceuticals from Dried Blood Spots using Digital Microfluidics” (P)
  6. Society for Laboratory Automation and Screening, Orlando, FL, USA, Jan 2013 “Digital microfluidics with impedance sensing for integrated cell culture and analysis” (L)
  7. Society for Laboratory Automation and Screening, Orlando, FL, USA, Jan 2013 “High Throughput Screening of Algal Lipids Using Digital Microfluidics” (P) [pdf]
  8. Institute of Biomaterial and Biomedical Engineering Scientific Day, Toronto, ON, Canada, May 2012. “Digital microfluidics with impedance sensing for integrated cell culture and analysis” (L).
  9. Micro Total Analysis Systems Symposium, Seattle, WA, US, Oct 2011. “Digital Microfluidics coupled to nanoelectrospray ionization mass spectrometry for succinylacetone analysis in dried blood spots” (P).
  10. Institute of Biomaterials and Biomedical Engineering Scientific Day, Toronto, ON, Canada, May 2011. “High Throughput Analysis of Algal Lipids Using Digital Microfluidics” (P).
  11. Biomedical Engineering Graduate Seminar Series (IBBME), Toronto, ON, Canada, Jan 2011. “Digital Microfluidics: Moving Microorganisms and Improving Droplet Control” (L).
  12. Micro Total Analysis Systems Symposium, Groningen, NL, Oct 2010. “A Feedback Control System for High-Fidelity Digital Microfluidics” (P).
  13. Micro Total Analysis Systems Symposium, Groningen, NL, Oct 2010. “Integrated Microbioreactor for Culture and Analysis of Bacteria, Algae and Yeast (Bay)” (P).
  14. Institute of Biomaterials and Biomedical Engineering Scientific Day, Toronto, ON, Canada, May 2010. “A feedback control system for high-fidelity digital microfluidics” (L).
  15. Institute of Biomaterial and Biomedical Engineering Scientific Day, Toronto, ON, Canada, May 2008. “Scalable strategies for reagent delivery in integrated microfluidic platforms” (P).
  16. XXII International Conference on Magnetic Resonance In Biological Systems, Gottigen, DE, Aug 2006. “Exploration of strategies for structure determination of multi-spanning helical membrane proteins by solution NMR” (P).
  17. McGill Biophysical Symposium, Montreal, QE, Canada, May 2006. “Exploration of strategies for structure determination of multi-spanning helical membrane proteins by solution NMR” (P).
  18. McGill Biophysical Symposium, Montreal, QE, Canada, May 2006. “Probing the membrane protein structure MCP in different detergents by solution NMR” (P).
  19. University of Ottawa Department of Chemistry Graduate Symposium, Ottawa, ON, Canada, Mar 2006. “Protein Folding in Solution vs. Gas Phase” (L).
  20. MOOT XVIII Symposium, Hamilton, ON, Canada, May 2005. “Structure calculation strategies for helical membrane protein determination by solution NMR” (P).